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Leucine is an amino acid that serves as one of the building blocks for protein synthesis. It is also an important metabolic trigger that turns on chemical pathways involved in protein synthesis. A study from the University of Tennessee found that supplementing 2.25 grams of leucine and 30 milligrams of vitamin B6 increased fat use by 30 grams a day. During a 12-week weight loss study, the supplement cause twice as much weight and fat loss as a low-calorie diet. When consuming a reduced-calorie diet, a supplement containing leucine and vitamin B6 can increase weight and fat loss by 50 to 80 percent.
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